Synthesis of thiadiazolinylpyrazolopyridine and pyridopyrazolotriazine derivatives

Article abstract of DOI:10.1002/jccs.200100130

3-Diazotized aminopyrazolo[3,4-b]pyridines 2a,b used as good synthons for the synthesis of 3-thiadiazolinylpyrazolo[3,4-b]pyridines 8a,b through their reactions with thiocyanatoacetophenone (6) and pyrido[2,3:3′,4′]pyrazolo[5,1-c][1,2,4]triazines 5a-d via their reactions with several active methylene containing reagents: 3a,b, 12, 16, 20, 23a-d and 26a-c. All the structures of the newly synthesized heterocyclic compounds were established by considering the data of IR, ¹H NMR and mass spectra in addition to the synthesis of most newly synthesized heterocyclic compounds via other routes.