Bioorganic and Medicinal Chemistry p. 1095 - 1105 (2016)
Update date:2022-09-26
Topics:
Carradori, Simone
Secci, Daniela
De Monte, Celeste
Mollica, Adriano
Ceruso, Mariangela
Akdemir, Atilla
Sobolev, Anatoly P.
Codispoti, Rossella
De Cosmi, Federica
Guglielmi, Paolo
Supuran, Claudiu T.
Small libraries of N-substituted saccharin and N-/O-substituted acesulfame derivatives were synthesized and tested as atypical and selective inhibitors of four different isoforms of human carbonic anhydrase (hCA I, II, IX and XII, EC 4.2.1.1). Most of the
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