Self-assembled arrays of dendrimer-gold-nanoparticle hybrids for functional cell studies

Article abstract of DOI:10.1002/anie.201006544

Dendrimer-controlled cell growth: A dendrimer-gold-nanoparticle hybrid array (see picture; PEG=polyethylene glycol), which can control the apparent dendrimer surface density, was used to investigate cell adhesion. The effect of the macromolecular architecture on the attachment and the morphological development of endothelial cells was studied. The dendrimer outperformed a linear counterpart, most likely modulated by the different interactions between the dendrimer and the proteins in the cell media. Copyright