Journal of Medicinal Chemistry p. 486 - 498 (2003)
Update date:2022-07-30
Topics:
Peukert, Stefan
Brendel, Joachim
Pirard, Bernard
Brüggemann, Andrea
Below, Peter
Kleemann, Heinz-Werner
Hemmerle, Horst
Schmidt, Wolfgang
The voltage-gated potassium channel Kv1.5 is regarded as a promising target for the development of new atrial selective drugs with fewer side effects. In the present study the discovery of ortho, ortho-disubstituted bisaryl compounds as blockers of the Kv
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(2002)
