CATALYTIC ASYMMETRIC HYDROGENATION OF β-DISUBSTITUTED α-PHENYLACRYLIC ACIDS. ASYMMETRIC SYNTHESIS OF CARBOXYLIC ACIDS CONTAINING TWO VICINAL CHIRAL CARBON CENTERS

Article abstract of DOI:10.1016/S0040-4039(00)82242-X

Hydrogenation of trisubstituted acrylic acids ((E)- and (Z)-MeC(R)=CPhCOOH: R = CD3, Et, Ph) in the presence of a chiral (aminoalkyl)ferrocenylphosphine-rhodium catalyst installed asymmetric configurations at two vicinal carbons at once giving optically a