Design, synthesis and biological evaluation of some 5-arylthieno[2,3-d]-pyrimidines as potential anti-cancer agents

Article abstract of DOI:10.1248/cpb.c16-00291

Structure-based design, synthesis and biological evaluation of new small molecules anti-cancer agents were described. On continuation of applying scaffold hopping theory, a series of 5-arylthieno[2,3-d]pyrimidines based on the structural features of lapat