The power of visual imagery in drug design. Isopavines as a new class of morphinomimetics and their human opioid receptor binding activity

Article abstract of DOI:10.1021/jm020164l

The importance of visual imagery and relational thinking manifests itself in a heuristic approach to the design and synthesis of potential morphinomimetics as agonists of the human-receptor. The well-known class of alkaloids represented by the isopavine n