Facile synthesis of α-anomeric pyrimidine nucleosides

Article abstract of DOI:10.1080/15257779408012178

2-Amino-α-D-ribofurano[1',2':4,5]-2-oxazoline reacted with α- bromoacrylonitrile yielding 2,2'-anhydro-1-α-D-ribofuranosylcytosine which was converted to α-cytidine and α-2'-deoxycytidine. Reaction of 2-amino- α-D-ribofurano[1',2':4,5]-2-oxazoline and ethyl α-(bromomethyl)acrylate afforded 2,2'-anhydro-1-α-D-ribofuranosylthymine, a precursor of α- thymidine and α-ribothymidine.

Full text of DOI:10.1080/15257779408012178

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Nucleosides and Nucleotides
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Facile Synthesis of α-Anomeric
Pyrimidine Nucleosides
Hiroaki Sawai a , Akiko Nakamura a , Hidekazu Hayashi a & Kazuo
Shinozuka a
a Department of Chemistry , Faculty of Engineering, Gunma
University , Kiryu, Gunma, 376, Japan
Published online: 24 Sep 2006.
To cite this article: Hiroaki Sawai , Akiko Nakamura , Hidekazu Hayashi & Kazuo Shinozuka (1994)
Facile Synthesis of α-Anomeric Pyrimidine Nucleosides, Nucleosides and Nucleotides, 13:6-7,
1647-1654, DOI: 10.1080/15257779408012178
To link to this article: http://dx.doi.org/10.1080/15257779408012178
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