Nucleosides and Nucleotides p. 1647 - 1654 (1994)
Update date:2022-08-03
Topics:
Sawai
Nakamura
Hayashi
Shinozuka
2-Amino-α-D-ribofurano[1',2':4,5]-2-oxazoline reacted with α- bromoacrylonitrile yielding 2,2'-anhydro-1-α-D-ribofuranosylcytosine which was converted to α-cytidine and α-2'-deoxycytidine. Reaction of 2-amino- α-D-ribofurano[1',2':4,5]-2-oxazoline and ethyl α-(bromomethyl)acrylate afforded 2,2'-anhydro-1-α-D-ribofuranosylthymine, a precursor of α- thymidine and α-ribothymidine.
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