Practical use of NH4X salts for difunctional oxyethylene-based intermediates

Article abstract of DOI:10.1016/j.tetlet.2007.05.081

A series of tosyl functionalized oxyethylene-based organic compounds were selected to analyze the scope and efficiency of a general substitution method for conversion to difunctional, soluble oxyethylene based intermediates using readily available ammonium salts, glycols and commercially modified ethoxy-ethanols. Straightforward preparation, product purification and low cost reagents are particularly advantageous for compounds incorporating halides, thiocyanates and methoxy groups.