Efficient synthesis of benz[c,d]indol-3(1H)-one derivatives by intramolecular cyclization of 3-(4′-methylcinnamoyl)indoles and subsequent elimination of toluene

DOI: 10.1515/HC.2003.9.2.119

Source and publish data:

Heterocyclic Communications p. 119 - 122 (2003)

Update date:2022-07-29

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Authors:

Komoda, Taichi

Nakatsuka, Shin-Ichi

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Article abstract of DOI:10.1515/HC.2003.9.2.119

Benz[c,d]indol-3(1H)-one 10 and 11, a major part of indole alkaloids 0231A 2 and 0231B 3 produced by Streptomyces sp. HKI0231, new enzyme inhibitors of 3α-hydroxysteroid dehydrogenase, were efficiently synthesized by cyclization of 3-(4′-methylcinnamoyl)indole derivatives 6c and 7c and elimination of toluene.

Full text of DOI:10.1515/HC.2003.9.2.119

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Article Doi

Efficient synthesis of benz[c,d]indol-3(1H)-one derivatives by intramolecular cyclization of 3-(4′-methylcinnamoyl)indoles and subsequent elimination of toluene

DOI: 10.1515/HC.2003.9.2.119

Source and publish data:

Authors:

Article abstract of DOI:10.1515/HC.2003.9.2.119

Full text of DOI:10.1515/HC.2003.9.2.119

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