Chemistry Letters p. 345 - 346 (1997)
Update date:2022-08-02
Topics: Solid-phase synthesis Yield NMR spectroscopy Bioassay Enantiomeric excess (ee) Chromatography Total synthesis Mass spectrometry (MS) High-performance liquid chromatography (HPLC) Deprotection Minimum inhibitory concentration (MIC) Protecting group Retrosynthetic analysis Structure-Activity Relationship (SAR) Peptide Coupling Chiral synthesis Stereocenter
Konda, Yaeko
Takahashi, Yukihiro
Mita, Hiroka
Takeda, Kazuyoshi
Harigaya, Yoshihiro
The first total synthesis of Mer-N5075A (1), a new potential HIV-I protease inhibitor produced from Streptomyces chromofuscus, was achieved. The synthetic method is available for Mer-N5075A analogues such as α-MAPI (2), GE20372 A (4) and other chemically
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Doi:10.1007/BF01185936
(1965)Doi:10.1016/S0040-4020(03)00543-X
(2003)Doi:10.1021/ja035901x
(2003)Doi:10.1016/S0957-4166(03)00308-2
(2003)Doi:10.1021/jo01339a026
(1966)Doi:10.1007/BF00958425
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