Efficient, Optimized Applications of p-Nitrophenyl Active Ester Temporarily Protecting Groups Together with Simultaneous Activation in Synthesis of Special Glu and Lys Peptides

Article abstract of DOI:10.1002/jccs.199700079

Benzyloxycarbonyl-glutamylpeptide p-nitrophenylesters were prepared from protected amino acids, e.g.: p-nitrophenyl-glutamate as carboxyl component and aminoacid or peptide p-nitrophenylesters as amino components by different kinds of peptide coupling met