A new class of diuretics with the 1,4 dioxino[2,3 g]quinolone structure

Article abstract of DOI:10.1021/jm00229a028

The authors have synthesized a number of new 2,3,6,9 tetrahydro 9 oxo 1,4 dioxino [2,3 g]quinoline 8 carboxylic acid derivatives. Surprisingly, some of these compounds proved to possess an extremely high diuretic activity.