One-pot synthesis of 2,4,5-triarylimidazoles catalyzed by copper (II) trifluoroacetate under solvent-free conditions

Article abstract of DOI:10.1080/15533171003629055

A simple, efficient and eco-friendly procedure has been developed using copper(II) trifluoroacetate as catalyst for the synthesis of 2,4,5-triarylimidazoles by one-pot condensation of benzil, aldehydes and ammonium acetate under solvent-free conditions. Compared with traditional methods, the present methodology offers several advantages such as excellent yields, and environmentally benign milder reaction conditions. Moreover, the catalyst exhibits reusable activity.