Journal of Medicinal Chemistry p. 449 - 452 (1977)
Update date:2022-08-05
Topics:
Diana
Banks Hinshaw
Lape
A series of 1-substituted 3,4-dihydroisoquinolines has been synthesized and screened for antihypertensive activity in the renal hypertensive rat. The 1-hydrazino homologue 6 and the corresponding acetaldehyde 25 and acetone 23 hydrazones exhibited good activity but were less effective than hydralazine 7.
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(1979)
