Journal of Medicinal Chemistry p. 449 - 452 (1977)
Update date:2022-08-05
Topics:
Diana
Banks Hinshaw
Lape
A series of 1-substituted 3,4-dihydroisoquinolines has been synthesized and screened for antihypertensive activity in the renal hypertensive rat. The 1-hydrazino homologue 6 and the corresponding acetaldehyde 25 and acetone 23 hydrazones exhibited good activity but were less effective than hydralazine 7.
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Doi:10.1016/S0040-4020(03)01104-9
(2003)Doi:10.1002/chem.200304880
(2003)Doi:10.1021/jm800180e
(2008)Doi:10.1016/j.bmcl.2007.12.014
(2008)Doi:10.1002/chem.201601707
(2016)Doi:10.1021/jm00189a004
(1979)
