Novel c-Met inhibitory olive secoiridoid semisynthetic analogs for the control of invasive breast cancer

DOI: 10.1016/j.ejmech.2016.04.043

Source and publish data:

European Journal of Medicinal Chemistry p. 299 - 315 (2016)

Update date:2022-08-15

Topics:

Authors:

Mohyeldin, Mohamed M.

Busnena, Belnaser A.

Akl, Mohamed R.

Dragoi, Ana Maria

Cardelli, James A.

El Sayed, Khalid A.

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Article abstract of DOI:10.1016/j.ejmech.2016.04.043

Dysregulated receptor tyrosine kinase c-Met and its ligand HGF is valid and attractive molecular target for therapeutic blockade in cancer. Inspired by the chemical structure of the naturally occurring olive secoiridoid (-)-oleocanthal (1) and its documen

Full text of DOI:10.1016/j.ejmech.2016.04.043

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