Organic Letters p. 4641 - 4644 (2003)
Update date:2022-08-05
Topics:
Crimmins, Michael T.
Siliphaivanh, Phieng
(Matrix presented) The enantioselective synthesis of the (+)-leucascandrolide A macrolactone has been achieved in 20 linear steps from 1,3-propanediol. The key steps in the synthesis are a reductive cleavage of bicyclic ketal 5 to establish the C15 stereo
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