A new total synthesis of (±)-clavulanic acid

DOI: 10.1016/S0040-4039(01)86869-6

Source and publish data:

Tetrahedron Letters p. 1889 - 1890 (1979)

Update date:2022-08-05

Topics:

Authors:

Bentley, Peter H.

Brooks, Gerald

Gilpin, Martin L.

Hunt, Eric

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Article abstract of DOI:10.1016/S0040-4039(01)86869-6

Regioselective reactions at the terminal double bond of the racemic azetidinone dienylether (4), provides a source of clavulanic acid and several analogues.

Full text of DOI:10.1016/S0040-4039(01)86869-6

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Product name:3-((Z)-2-hydroxy-ethylidene)-7-oxo-(5rH)-4-oxa-1-aza-bicyclo[3.2.0]heptane-2c-carboxylic acid methyl ester

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