Synthesis of tetracyclic heterocompounds as selective estrogen receptor modulators. Part 1. Process development for scale-up of 2,5,8-substituted 5,11 -dihydrochromeno[4,3-c]chromene derivatives

DOI: 10.1021/op700020f

Source and publish data:

Organic Process Research and Development p. 414 - 421 (2007)

Update date:2022-07-29

Topics:

Authors:

Li, Xun Li, Xun

Reuman, Michael

Russell, Ronald K.

Adams, Richard

Ma, Robert

Beish, Sandra

Branum, Shawn

Youells, Scott

Roberts, Jerry

Jain, Nareshkumar

Kanojia, Ramesh

Sui, Zhihua

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/op700020f

Unsymmetrical benzopyranobenzopyran compounds are novel selective estrogen receptor modulators (SERMs). A reproducible and nonchromatographic process was developed to prepare multihundred gram quantities of 5-(4-(2-(piperidin-1-yl) ethoxy)-phenyl)-5,11-di

Full text of DOI:10.1021/op700020f

Products guided by the article

Product name:4-[(2,4-dimethoxy-phenyl)-thioacetyl]-morpholine

Cas No:6496-88-4

R&D Labs maybe for 6496-88-4

Kaiping Genuine Biochemical Pharmaceutical Co.,Ltd.

Contact:+86-750-2881198

Address:No.1, Xinke Road, Shatang Town, Kaiping, Guangdong Province, P.R.China
Anhui Charm Imp.&Exp.Co., Ltd

website:http://www.chinacharm.cn/

Contact:86 551 5316260

Address:No. 211,XiangZhang Road,Hefei City,Anhui Province,China
Shanghai Standard Biotech Co., Ltd.

Contact:+86-18502101150

Address:Room 103, Building 2nd, NO.720, Cailun Road , Pudong District, Shanghai, China
PharmaResources(Kaiyuan)CO,.Ltd

Contact:+86-21-50720028

Address:No.3, Beihuan Road, Economic Development District, Kaiyuan City, Tieling City, Liaoning Province, China 112300
Wuhan Jadechem International Trade Co.,Ltd.

website:http://www.jadechem-intl.com

Contact:+86-27-83527060

Address:Room 502,Building C11,Software new city No.8,Huacheng Avenue,East Lake High-tech development zone,Wuhan,Hubei,China

Relevant to this article

Monomerisation of [Rh₂(1,3-bis-(diphenylphosphino)-propane)₂(μ₂-Cl)₂] detected by pulsed gradient spin echo spectroscopy and ³¹P NMR monitoring of metathesis experiments

Doi:10.3184/174751918X15333065984578
(2018)
Direct Covalent Grafting of Conjugated Molecules onto Si, GaAs, and Pd Surfaces from Aryldiazonium Salts

Doi:10.1021/ja0383120
(2004)
Synthesis of substituted cis-bicyclo[3.3.0]octane-1-carbonyl derivatives by stereospecific rearrangement of 1-chloro-9-hydroxybicyclo [3.3.1] nonanes

Doi:10.1016/S0040-4020(01)86512-1
(1991)
Doi:10.1016/0040-4020(77)80260-3
(1977)
Thieme Chemistry Journals Awardees - Where Are They Now? Rhodium-Catalyzed Synthesis of Unsymmetric Di(heteroaryl) Ethers Using Heteroaryl Exchange Reaction

Doi:10.1055/s-0036-1588801
(2017)
Synthesis of β-amino alcohols using MgO as a new catalyst under solvent-free conditions

Doi:10.1139/V07-135
(2008)

Article Doi