New 1,4-dihydropyridine derivatives combining calcium antagonism and α-adrenolytic properties

DOI: 10.1021/jm00126a042

Source and publish data:

Journal of Medicinal Chemistry p. 1402 - 1407 (1989)

Update date:2022-07-30

Topics:

Authors:

Marciniak

Delgado Delgado

Leclerc Leclerc

Velly Velly

Decker Decker

Schwartz

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Article abstract of DOI:10.1021/jm00126a042

A series of twelve 1,4-dihydropyridine derivatives incorporating an α-adrenergic moiety in one of the ester chains was synthesized. The compounds were evaluated for their calcium antagonist activities by the inhibition of [³H]nitrendipine bindi

Full text of DOI:10.1021/jm00126a042

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