Synthesis and Resolution of 1-(2-Diphenylphosphino-1-naphthyl)isoquinoline; a P-N Chelating Ligand for Asymmetric Catalysis

DOI: 10.1016/S0957-4166(00)80183-4

Source and publish data:

Tetrahedron Asymmetry p. 743 - 756 (1993)

Update date:2022-08-04

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Authors:

Alcock, Nathaniel W.

Brown, John M.

Hulmes, David I.

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Article abstract of DOI:10.1016/S0957-4166(00)80183-4

A multistep synthesis resulting in a good yield of the title compound has been developed based on the Pd-catalysed coupling of 1-chloroisoquinoline and 2-methoxy-1-naphthylboronic acid (5).The product is converted into the corresponding trifluoromethanesu

Full text of DOI:10.1016/S0957-4166(00)80183-4

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