Characterization of autoxidation products of the antifungal compounds econazole nitrate and miconazole nitrate

DOI: 10.1016/S0040-4020(01)82309-7

Source and publish data:

Tetrahedron p. 6549 - 6560 (1991)

Update date:2022-08-02

Topics:

Authors:

Oyler Oyler

Naldi Naldi

Facchine

Burinsky

Cozine Cozine

Dunphy Dunphy

Alves-Santana

Cotter Cotter

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4020(01)82309-7

Econazole nitrate 1 and miconazole nitrate 2 underwent autoxidation in 90% ethanol at 77°C in the presence of AIBN and oxygen. The benzylic methylene carbons of 1 and 2, the benzylic methine carbon of 2, and the imidazole ring of 2 were sites of oxidation.

Full text of DOI:10.1016/S0040-4020(01)82309-7

Products guided by the article

Product name:4-Chloro-benzoic acid 1-(2,4-dichloro-phenyl)-2-imidazol-1-yl-ethyl ester; compound with nitric acid

Cas No:68571-12-0

R&D Labs maybe for 68571-12-0

Wuhan Benjamin Pharmaceutical Chemical Co.,Ltd

Contact:86-27-52341789

Address:Room 1518 B suite, optical valley time square, No 111 Guanshan Road, Hongshan District,Wuhan,Hubei Province,China.
Shanghai Kangxin Chemical Co., Ltd

Contact:+86 21 60717227

Address:118,Ganbai Village,Waigang Town,Jiading District,Shanghai
Synchem Pharma Co.,Ltd(expird)

Contact:+0086-21-61984905-1

Address:Building 60,Zimian Park, LongYang industrial Area, 1515Nong，Yuandong Road Fengxian District, Shanghai ,China
Guangzhou Swan Chemical Co., Ltd.

Contact:+86-20-31075659

Address:NO.301, Hong ba fang investment BLDG 1,Guan chong village,Shiqi town,Panyu district,Guangzhou
Hunan Haili Chemical Industry Co.,Ltd.

Contact:+86-731-85521860

Address:No.251, 2nd Section, Furong Road, Changsha,Hunan,China

Relevant to this article

DRIFTS and optical microscopic study of the solventless reaction between (η⁵-C₅H₅)M(CO)₃CH₃ (M = Mo, W) and L (L = P(p-FC₆H₄)₃, P(C ₆H₅)₃)

Doi:10.1021/om0343869
(2004)
Doi:10.1021/jo01320a005
(1979)
pH Dependency of the Zinc and Cobalt Carboxypeptidase Catalyzed Enolization of (R)-2-Benzyl-3-(p-methoxybenzoyl)propionic Acid

Doi:10.1021/ja00349a055
(1983)
Stereoselective [2,3] sigmatropic rearrangement of acyclic allylic phosphinites

Doi:10.1039/b313979d
(2004)
Titanium-mediated cross-coupling reactions of imines with ketones or aldehydes: An efficient route for the synthesis of 1,2-amino alcohols

Doi:10.1016/j.tetlet.2012.07.020
(2012)
The use of temporary tethers in the meta photocycloaddition reaction

Doi:10.1016/j.tet.2004.01.065
(2004)

Article Doi