Tetrahedron p. 6549 - 6560 (1991)
Update date:2022-08-02
Topics:
Oyler
Naldi
Facchine
Burinsky
Cozine
Dunphy
Alves-Santana
Cotter
Econazole nitrate 1 and miconazole nitrate 2 underwent autoxidation in 90% ethanol at 77°C in the presence of AIBN and oxygen. The benzylic methylene carbons of 1 and 2, the benzylic methine carbon of 2, and the imidazole ring of 2 were sites of oxidation.
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