Enantioselective desymmetrization of meso-aziridines with aromatic thiols catalyzed by chiral bifunctional quaternary phosphonium salts derived from α-amino acids

Article abstract of DOI:10.1016/j.tet.2015.02.001

Desymmetrization of meso-aziridines with aromatic thiols was realized by using α-amino acids-derived chiral quaternary phosphonium salts catalysts to provide chiral β-amino sulfides with high yields (up to 99%) and in moderate enantioselectivities (up to