An efficient synthesis of trihydroxy quinolizidine alkaloids using ring-closing metathesis

Article abstract of DOI:10.1055/s-2004-829538

The sequential C- and N-allylation of D-glucose-derived nitrone 2 provides the required diene functionality with nitrogen linker that was used in ring-closing metathesis pathway in the synthesis of quinolizidine alkaloids 1a and 1b.