A cleavage of some hydroxybenzyl(α-amino)-phosphonates in a basic medium

Article abstract of DOI:10.1080/10426509808045493

α-Aminobenzylphosphonic acids possessing the hydroxy groups in ortho and para positions, underwent a C-P bond cleavage during heating with aqueous NaOH solution. In the case of o- and p-hydroxy diethyl esters 1 and 3 the products of the cleavage were the corresponding aldehydes and phosphorous acid (H₃PO₃). The m-hydroxy derivative was not affected by a base. It has been found, that displacement of the hydroxy group by the methoxy one in the p-hydroxybenzyl(α-amino)phosphonic acid leads to a stability of such a compound towards a base; no a C-P bond cleavage was observed in this case.

Full text of DOI:10.1080/10426509808045493

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Phosphorus, Sulfur, and Silicon
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A CLEAVAGE OF SOME
HYDROXYBENZYL(α-AMINO)-
PHOSPHONATES IN A BASIC
MEDIUM
Bogdan Boduszek a & Agnieszka Halama a
a Institute of Organic Chemistry, Biochemistry and
Biotechnology, Wroclaw University of Technology ,
50-370, Wroclaw, Poland
Published online: 04 Oct 2006.
To cite this article: Bogdan Boduszek & Agnieszka Halama (1998) A CLEAVAGE
OF SOME HYDROXYBENZYL(α-AMINO)-PHOSPHONATES IN A BASIC MEDIUM,
Phosphorus, Sulfur, and Silicon and the Related Elements, 143:1, 151-158, DOI:
10.1080/10426509808045493
To link to this article: http://dx.doi.org/10.1080/10426509808045493
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