Extractive biocatalysis: A powerful tool in selectivity control in yeast biotransformations

Article abstract of DOI:10.1016/S0040-4020(98)00941-7

The effect of absorbing resins on the yeast reduction of α,β- unsaturated carbonyl compounds is reported. Enantioselectivity, chemoselectivity and space-time yields of the biotransformation are impressively enhanced. The distribution of substrates and products between the resin and the water phase shows that the improved selectivity has to be attributed to the control of substrate concentration.