
Journal of Organic Chemistry p. 3382 - 3387 (1980)
Update date:2022-07-31
Topics:
Sundberg, Richard J.
Bloom, Jonathan D.
20-Deethylcatharanthine, a potential precursor of vinblastine-type dimeric indole alkaloids, has been synthesized in ten steps from 1-benzenesulfonylindole.The Synthesis features a Diels-Alder reaction between 1-carbethoxy-1,2-dihydropyridine and ethyl 2-
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