Aporphines. 27. Mechanistic Aspects of the Rearrangement of Thebaine and Codeine Analogues in Methanesulfonic Acid. Improved Method for Synthesis of N-Alkylated Aporphines

DOI: 10.1021/jo01300a001

Source and publish data:

Journal of Organic Chemistry p. 2275 - 2278 (1980)

Update date:2022-08-05

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Authors:

Granchelli, Felix E.

Filer, Crist N.

Soloway, Albert H.

Neumeyer, John L.

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Article abstract of DOI:10.1021/jo01300a001

The rearrangement of thebaine (1a), northebaine (1b), and N-(2-hydroxyethyl)northebaine (1c) in methanesulfonic acid leading to the formation of novel N-alkylated-2-O-methylated normorphothebaine derivatives 4a-c was investigated.We have observed that a s

Full text of DOI:10.1021/jo01300a001

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