γ-Alkylation of α,β-Unsaturated Ketones. γ-Arylsulfonyl Groups as Regioselective Control Elements

Article abstract of DOI:10.1021/ja00525a023

A reaction sequence for γ-alkylation of α,β-unsaturated ketones has been proposed and tested with some success. γ-(Phenylsulfonyl) groups are (1) introduced into the substrate; (2) present during alkylation of the resulting highly delocalized carbanions; (3) finally removed to leave the otherwise inaccessible γ-alkylation product.