One-pot synthesis of new 6-pyrrolyl-N-alkyl-indazoles from reductive coupling of N-alkyl-6-nitroindazoles and 2,5-hexadione

DOI: 10.1016/j.tetlet.2015.11.071

Source and publish data:

Tetrahedron Letters p. 113 - 117 (2016)

Update date:2022-08-05

Topics:

Authors:

El Ghozlani, Mohamed

Chicha, Hakima

Abbassi, Najat

Chigr, Mohamed

El Ammari, Lahcen

Saadi, Mohamed

Spinelli, Domenico

Rakib, El Mostapha

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Article abstract of DOI:10.1016/j.tetlet.2015.11.071

One-pot synthesis of 6-pyrrolyl-N-alkyl-indazoles by the reductive coupling of N-alkyl-6-nitroindazoles and 2,5-hexadione was investigated in the presence of different reducing agents (SnCl₂/AcOH and In/AcOH in THF). Indazoles 5a-h and 6a-h wer

Full text of DOI:10.1016/j.tetlet.2015.11.071

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