Bioorganic and Medicinal Chemistry Letters p. 3401 - 3406 (2004)
Update date:2022-08-03
Topics:
Bloom, Jonathan D.
Dushin, Russell G.
Curran, Kevin J.
Donahue, Fran
Norton, Emily B.
Terefenko, Eugene
Jones, Thomas R.
Ross, Adma A.
Feld, Boris
Lang, Stanley A.
DiGrandi, Martin J.
A series of highly potent thiourea inhibitors of cytomegalovirus (CMV) with improved stability properties was prepared and evaluated. Compound 29 inhibited the virus in cultured HFF cells with IC50 of 0.2nM.
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