Tetrahedron Letters p. 5881 - 5882 (1989)
Update date:2022-07-31
Topics:
Nasioulas, Georgios
Grammbitter, Klaus
Gerzon, Koert
Ponstingl, Herwig
The synthesis of 3-<<<2-amino(4-azido-2-nitrophenyl)ethyl>amino>carbonyl>-O4-deacetyl-3-de(methoxycarbonyl)-vincaleukoblastine (napavin) from vinblastine is described.This new photoreactive cytoststatic substance overcomes multidrug resistance
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