Journal of the Chemical Society. Perkin transactions I p. 690 - 692 (1980)
Update date:2022-08-04
Topics:
Berge, John M.
Roberts, Stanley M.
Suschitzky, Hans
Kemp, John E. G.
The epoxide ring in the β-lactams (2) and (3) was opened regioselectively with aqueous hydroiodic acid; attack by iodide occurred at C-3 preferentially.Thiophenolate ions attacked the epoxy-lactam (2) at C(4) with high selectivity while the epoxide (3) was attacked at C(3) exclusively.The differing selectivities of attack by nucleophiles at the epoxide units are explained in terms of an interplay of steric and electronic impositions owing to the neighbouring β-lactam ring.
View MoreGuangzhou Swan Chemical Co., Ltd.
Contact:+86-20-31075659
Address:NO.301, Hong ba fang investment BLDG 1,Guan chong village,Shiqi town,Panyu district,Guangzhou
Contact:+91 - 22 - 26355700
Address:17, Lotus Business Park, Andheri West
Zhejiang Chemicals Import & Export Corporation (ZHECHEM)
Contact:+86-571-87046953
Address:No. 37, Qingchun Road
Contact:732.938.2777
Address:5012 Industrial Road Farmingdale, NJ 07727
Jinan Jianfeng Chemical Co., Ltd
Contact:0086-531-88110457
Address:sales01(-a-t-)pharmachemm{dot}c+o+m
Doi:10.1007/BF01435827
(1996)Doi:10.1246/bcsj.53.1769
(1980)Doi:10.1021/ja01543a036
(1958)Doi:10.1021/jo01313a017
(1980)Doi:10.1016/S0022-328X(00)90641-7
(1980)Doi:10.1016/0040-4039(80)80107-9
(1980)
