Journal of the Chemical Society. Perkin transactions I p. 690 - 692 (1980)
Update date:2022-08-04
Topics:
Berge, John M.
Roberts, Stanley M.
Suschitzky, Hans
Kemp, John E. G.
The epoxide ring in the β-lactams (2) and (3) was opened regioselectively with aqueous hydroiodic acid; attack by iodide occurred at C-3 preferentially.Thiophenolate ions attacked the epoxy-lactam (2) at C(4) with high selectivity while the epoxide (3) was attacked at C(3) exclusively.The differing selectivities of attack by nucleophiles at the epoxide units are explained in terms of an interplay of steric and electronic impositions owing to the neighbouring β-lactam ring.
View MoreShaanxi King Stone Enterprise Company Limited
Contact:86-29-88353805,13609285751
Address:.209 Keji Road Hi-Tech industrial Develpment Zone .Xian China
Shandong Jiulong Hisince Pharmaceutical Co.,Ltd.
Contact:+86-15853188990
Address:Huadian Pioneer Park, Huadian Township, Qihe County, Dezhou City, Shandong, P.R.China
website:http://www.cartoonchem.com/
Contact:+86-25-58074918
Address:Room 2109, RuiHua Business Center,315 South ZhongShan Road, Nanjing 210001, China
Zhejiang Rongkai Chemical Technology Co.,Ltd.
Contact:+86-578-8185786
Address:Shangjiang Industrial Zone,Suichang
Nanjing Vincero International Trading Co.,Ltd
Contact:8618936897229
Address:NO.68, ZhuShan Road, JiangNing WanDa Plaza, Building E Room 1703
Doi:10.1007/BF01435827
(1996)Doi:10.1246/bcsj.53.1769
(1980)Doi:10.1021/ja01543a036
(1958)Doi:10.1021/jo01313a017
(1980)Doi:10.1016/S0022-328X(00)90641-7
(1980)Doi:10.1016/0040-4039(80)80107-9
(1980)
