Journal of Medicinal Chemistry p. 1826 - 1830 (1995)
Update date:2022-08-04
Topics:
Kumar, Virendra
Carbateas, Phil M.
Dority, John A.
Earley, William G.
Mallamo, John P.
et al.
Replacement of the pyridinium ring of 6,11-ethanobenzoquinolizinium cations with thiazolium (4a and 4b) and N-methylimidazolium (4c and 4d) resulted in equipotent compounds in the <3H>TCP binding assay.The corresponding N-methyl-1,2,4-triazolium analogs were less potent in this assay.The thiazolium derivative 4b, with a Ki = 2.9 nM, is being evaluated as a possible neuroprotective N-methyl-D-aspartic acid (NMDA) anatgonist.
View MoreShandong Xingshun New Material Co., Ltd.
website:http://www.sd-xingshun.com
Contact:+86-519-86461196
Address:Middle of Luhua East Road, Dingtao District
Hangzhou Dingyan Chem Co., Ltd
website:http://www.dingyanchem.com
Contact:86-571-87157530
Address:RM.1118,NO.1 Building, Baiyun Tower,Jianggan Area, Hangzhou city, China,310004
JiangXi Hong Run Chemical Co., Ltd
Contact:+86-0791-88521351
Address:XingHuo industrial zone in YongXiu county
Zhejiang Golden-Shell Pharmaceutical Co.,Ltd.
Contact:+86-576-87501888 / 87501988
Address:No.89 Zhongxing Road. Li'ao, Yuhuan, Zhejiang, China
Jiangsu Dacheng Pharmaceutical and Chemical Co.,Ltd
Contact:+86-0517-87036900
Address:Chuzhou Chemical park, Huai'an, Jiangsu Province
Doi:10.1016/S0022-328X(00)86664-4
(1980)Doi:10.1007/BF02464191
(1998)Doi:10.1021/jo00314a031
(1981)Doi:10.1081/SIM-120030430
(2004)Doi:10.1016/S0022-328X(00)85395-4
(1969)Doi:10.1016/S0020-1693(00)80821-X
(1989)
