
Journal of Medicinal Chemistry p. 381 - 392 (1983)
Update date:2022-07-29
Topics:
McEvoy, Francis J.
Lai, Fong M.
Albright, J. Donald
A series of 1-<3-(acylthio)-3-aroylpropionyl>-L-proline derivatives was synthesized.A number of these compounds are potent angiotensin converting enzyme (ACE) inhibitors that lowered blood pressure in aorta-coarcted renal hypertensive rats.The most active
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