Journal of Medicinal Chemistry p. 104 - 109 (1981)
Update date:2022-09-26
Topics:
Klutchko, Sylvester
Hoefle, Milton L.
Smith, Ronald D.
Essenburg, Arnold D.
Parker, Robert B.
et al.
A number of γ- and δ-lactam derivatives were synthesized and their in vitro angiotensin-converting enzyme (ACE) inhibitory activities were compared.The structures of these compounds were designed to include many of the important features of captopril.The
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