Journal of Organometallic Chemistry p. 139 - 147 (1981)
Update date:2022-08-03
Topics:
Marsais, Francis
Breant, Patrice
Ginguene, Alain
Queguiner, Guy
Lithium dialkylamides metalate 3-chloropyridine with excellent regioselectivity at position 4.This reaction occurs in THF solution at -60 deg C and it leads to various 3,4-disubstituted pyridines in good yields.This regioselectivity is completely changed in ether solution by using the butyllithium-TMEDA complex.In that case position 2 is metallated and 2,3-disubstituted pyridines are obtained.
View MoreJiangsu Zenji Pharmaceuticals LTD
Contact:+86-025-83172562; +1-224-888-1133(USA)
Address:No.5 Xinmofan Road
Contact:+86-21-56338808
Address:799 Dunhuang Road, Putuo
Beijing Mashi Fine Chemical Co.,Ltd.
Contact:+86-10-61271592
Address:Room 506, Section B, Kaichi Mansion, Industrial Development
SHANXI XINTIANYUAN PHARMACEUTICAL CO., LTD.
website:http://www.tychemical.com
Contact:0086-358-3521713 3521715
Address:No. 1 Yintong Road, Shanxi Jiaocheng Economic Development Zone, Xiajiaying Town, Jiaocheng County, Lvliang City, Shanxi Province, China
Beijing Green Guardee Technology CO,.LTD
Contact:+86-10-69706062
Address:F2 BLdj,5 No.37 Chaoqian Road
Doi:10.1021/jo00328a016
(1981)Doi:10.1016/j.ejphar.2004.06.038
(2004)Doi:10.1021/om0343824
(2004)Doi:10.1021/jm00197a011
(1979)Doi:10.1016/j.tetlet.2005.03.027
(2005)Doi:10.1016/0040-4039(81)80075-5
(1981)
