Tetrahedron Letters p. 4137 - 4140 (1980)
Update date:2022-08-04
Topics:
Gribble, Gordon W.
Saulnier, Mark G.
Regioselective ortho lithiation of 2-, 3-, and 4-halopyridines is achieved with lithium diisopropylamide (-78°, tetrahydrofuran) to afford, upon quenching with electrophilic reagents, 2,3- and 3,4-disubstituted pyridines in good to excellent yield.
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(2013)Doi:10.1021/jo00329a019
(1981)Doi:10.1021/jo00148a025
(1982)Doi:10.1021/jm00138a002
(1981)Doi:10.1021/ol9013156
(2009)Doi:10.1021/jm00307a011
(1968)
