A NEW METHOD FOR ENANTIOSELECTIVE SYNTHESIS OF β-HYDROXY-α-AMINO ACIDS

DOI: 10.1246/cl.1981.279

Source and publish data:

Chemistry Letters p. 279 - 282 (1981)

Update date:2022-08-02

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Authors:

Nakatsuka, Takashi

Miwa, Tetsuo

Mukaiyama, Teruaki

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Article abstract of DOI:10.1246/cl.1981.279

Highly optically active threo-β-hydroxy-α-amino acids were obtained by the successive treatment of the chiral hydroxy imine 1, prepared by the condensation of t-butyl glycinate with a chiral ketol 3, with methylmagnesium iodide, potassium diisopropylamide

Full text of DOI:10.1246/cl.1981.279

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