STEREOCONTROLLED SYNTHESIS OF 7-HYDROXY- AND 7-ACETOXY-PGI2: NEW STABLE PGI2 ANALOGUES

DOI: 10.1016/S0040-4039(01)90337-5

Source and publish data:

Tetrahedron Letters p. 1417 - 1420 (1981)

Update date:2022-08-04

Topics:

Authors:

Bannai, Kiyoshi

Toru, Takeshi

Oba, Takeo

Tanaka, Toshio

Okamura, Noriaki

et al. et al.

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Article abstract of DOI:10.1016/S0040-4039(01)90337-5

Stable analogues of PGI₂, 7-hydroxy- and 7-acetoxy-PGI₂, were synthesized from protected PGI₂ methyl ester 1b via sulfoxides 6a, 6b through stereocontrlled sulfoxide-sulfenate rearrangement.

Full text of DOI:10.1016/S0040-4039(01)90337-5

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