Iodine catalyzed simple and efficient synthesis of antiproliferative 2-pyridones

Article abstract of DOI:10.1016/j.bmcl.2016.03.071

A simple and efficient method for the selective synthesis of 2-pyrdones from 4H-pyrans using iodine as catalyst and ethanol as solvent was developed. The present method is equally effective for both aromatic and hetero aromatic ring containing 4H-pyrans.