Carbonylation of Aryllithium Reagents in the Presence of Alkly Halides: One-Pot Synthesis of Diarylalkylcarbinols and Derivatives

Article abstract of DOI:10.1021/jo00335a080

The carbonylation of ArLi (Ar = Ph, o-anisyl) in the presence of alkyl bromides affords diarylalkylcarbinols in good yields.The reaction may be used to obtain alcohols functionalized in the alkyl chain; it can also be adapted to afford substituted tetrahydrofurans.