
Journal of Medicinal Chemistry p. 373 - 381 (1983)
Update date:2022-09-26
Topics:
Yamada, Toshihiro
Nobuhara, Youichi
Shimamura, Hiroshi
Tsukamoto, Yoshitsugu
Yoshihara, Kazuo
et al.
In an effort to develop new types of antiulcer agents, we synthesized a series of novel 2-<ω-(thioureido)alkyl>- and 2-<ω-(cyanoguanidino)alkyl>-3-(2H)-pyridazinone derivatives.All target compounds were evaluated for gastric antisecretory activity in the
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Doi:10.1016/S0008-6215(00)81880-7
(1981)Doi:10.1016/j.tetasy.2004.08.013
(2004)Doi:10.1021/jm040092t
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(1982)Doi:10.1021/acs.orglett.9b03471
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(1982)