Helvetica Chimica Acta p. 1303 - 1311 (1981)
Update date:2022-08-03
Topics:
Ernest, Ivan
Main, Alan J.
Woodward, Robert B.
Selective formation - in intramolecular Wittig condensations - of the 2-oxocephem-4-carboxylate 8a and of the 2-acetylpenem-3-carboxylate 9, respectively, was observed as a consequence of different carbonyl reactivities in two homologous α-oxoacylthio groupings.Free, racemic and 7-unsubstituted 2-oxocephem-4-carboxylic acid (10) was prepared from 8a for biological testing.Attempts to prepare the free 2-acetylpenem-3-carboxylic acid from 9 failed, probably due to the high lability of the β-lactam system.
View MoreWuhan Sunrise Pharmaceutical Technology Co., Ltd
Contact:+86-27-83314682
Address:Room 340, New material Industrial base No.17, Gu Tian Five Lu , Qiaokou District, Wuhan , China
A.M FOOD CHEMICAL CO., LIMITED
Contact:86-531-87100375
Address:20Floor，Bblock，1Building，pharma-valley，Jinan，China
website:http://www.np-chem.com
Contact:0086-25-52346877
Address:199, Jian Ye Road, Nanjing, China
Contact:86-21-34622192，13917187091，21-34622765
Address:No. 500 Caobao Road Shanghai P.R China
Contact:+852-8198 2399
Address:9E, Leapont Industrial Building, 18-28 Wo Liu Hang Road, Shatin, New Territories, Hong Kong
Doi:10.1021/jo049154d
(2004)Doi:10.3390/molecules21111602
(2016)Doi:10.1016/j.molcata.2004.12.024
(2005)Doi:10.1021/jo00341a027
(1982)Doi:10.1016/j.bmc.2004.07.055
(2004)Doi:10.1246/cl.1982.597
(1982)
