Spectroscopic Study of the Interaction of 1-(Di-n-propylamino)-2,6-dinitro-4-(trifluoromethyl)benzene with Amines

Article abstract of DOI:10.1021/jo00341a028

The reactions of 4 with amines and amino acids in Me2SO-H2O solutions have been studied by NMR and UV-vis spectroscopy, and kinetic parameters have been determined.In the presence of 1 equiv of OH^-, 1:1 ? complexes were formed, but there was no evidence for 1:2 comlexes.Spectral and kinetic data indicate that the initial reaction product is a 1,3 ? complex and that in H2O-rich solvent mixtures this complex is slowly converted into the isomeric 1,1 ? complex.Equillibrium constants for the reactions of 4 with n-BuNH2 and with piperidine have been determined.