STEREOCONTROLLED SYNTHESIS OF α,β-UNSATURATED CARBOXYLIC ESTERS FROM O-METHYL-C,O-BIS(TRIMETHYLSILYL)KETENE ACETAL AND ALIPHATIC ALDEHYDES

Article abstract of DOI:10.1016/S0040-4039(01)90445-9

(R^*,S^*) Selective aldol type reaction of O-methyl-C,O-bis(trimethylsilyl)ketene acetal (1) with aldehydes and stereoselective formation of α,β-unsaturated carboxylic esters are attained by the combination of Z-1 and Lewis acids.