Cyclization of ortho-Halogenated N-Acylbenzylamines: a Formal Synthesis of (+/-)-Cherylline

DOI: 10.1039/c39810001074

Source and publish data:

Journal of the Chemical Society. Chemical communications p. 1074 - 1075 (1981)

Update date:2022-08-04

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Authors:

Kessar, Satinder V.

Singh, Paramjit

Chawla, Ravinder

Kumar, Pawan

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Article abstract of DOI:10.1039/c39810001074

ortho-Halogenated N-alkyl-N-acylbenzylamines can be cyclised to dihydroisoquinolones by reaction with KNH2 in liquid NH3 or lithium di-isopropylamide in tetrahydrofuran under photolytic and thermal conditions; the procedure has been employed to synthesize

Full text of DOI:10.1039/c39810001074

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