Tetrahedron p. 10779 - 10786 (2004)
Update date:2022-08-04
Topics:
Jones, Ashley W.
Purwono, Bambang
Bowyer, Paul K.
Mitchell, Peter S.R.
Kumar, Naresh
Nugent, Stephen J.
Jolliffe, Katrina A.
Black, David StC.
A range of 3-substituted-4,6-dimethoxyindoles bearing electron-withdrawing groups in either the 2- or 7-position, can be nitrated using nitric acid adsorbed on silica, to give 7-nitro and 2-nitro-indoles, respectively. A 1-cyano-indole gives regioselectiv
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