Stereospecific synthesis of clomiphene and tamoxifen via stannylcupration of diphenylacetylene

Article abstract of DOI:10.1080/00397919508011484

Stereospecific trans-stannylcupration of diphenylacetylene affords a 1,2-dimetallostilbene which may be elaborated into either Clomiphene or Tamoxifen through palladium-catalyzed coupling with an aryl iodide.

Full text of DOI:10.1080/00397919508011484

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Synthetic Communications: An
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Organic Chemistry
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Stereospecific Syntheses of
Clomiphene and Tamoxifen
via Stannylcupration of
Diphenylacetylene
Clark H. Cummins a
a Dow Chemical Company, Central Research and
Development - Materials Research and Development
Laboratory, Building 1707, Midland, MI, 48674
Version of record first published: 23 Sep 2006.
To cite this article: Clark H. Cummins (1995): Stereospecific Syntheses of Clomiphene
and Tamoxifen via Stannylcupration of Diphenylacetylene, Synthetic Communications:
An International Journal for Rapid Communication of Synthetic Organic Chemistry,
25:24, 4071-4079
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