INTRODUCTION OF CARBON UNIT AT THE α-POSITION OF ALICYCLIC AMINES UTILIZING A DECARBOXYLATION REACTION WITH MALONIC ACID DERIVATIVES

Article abstract of DOI:10.1246/cl.1982.231

A new method for introducing carbon unit at the α-position of alicyclic amines has been exploited.The method involves a reaction of trimers of alicyclic imines with malonic acid derivatives, of which decarboxylation leads to a formation of carbon-carbon bond at the α-position of alicyclic amines.